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Antibiotic Treatment

Periodontal disease is a progressive condition which leads to severe inflammation and tooth loss if left untreated.  Antibiotic treatments can be used in combination with scaling and root planning, curettage, surgery or as a stand-alone treatment to help reduce bacteria before and/or after many common periodontal procedures.

Antibiotic treatments come in several different types, including oral forms and topical gels which are applied directly into the gum pockets.  Research has shown that in the case of acute periodontal infection, refractory periodontal disease, prepubertal periodontal disease and juvenile periodontal disease, antibiotic treatments have been incredibly effective.

Antibiotics can be prescribed at a low dose for longer term use, or as a short term medication to deter bacteria from re-colonizing.

Oral Antibiotics

Oral antibiotics tend to affect the whole body and are less commonly prescribed than topical gel.  Here are some specific details about several different types of oral antibiotics:

  • Tetracycline antibiotics – Antibiotics which include tetracycline hydrochloride, doxycycline, and minocycline are the primary drugs used in periodontal treatment.  They have antibacterial properties, reduce inflammation and block collagenase (a protein which destroys the connective tissue).

  • Macrolide antibiotics – This group of antibiotics has proven effective at reducing inflammation, and can also reduce bacterial growth associated with periodontitis.

  • Metronidazole – This antibiotic is generally used in combination with amoxicillin or tetracycline to combat inflammation and bacterial growth in severe or chronic periodontitis.

Topical Gels and Strips

The biggest advantage of the direct delivery of antibiotics to the surfaces of the gums is that the whole body is not affected.  Topical gels and direct delivery methods tend to be preferred over their oral counterparts and are extremely effective when used after scaling and root planing procedures. Here are some of the most commonly used direct delivery antibiotics:

  • Atridox® – This doxycycline gel conforms to the contours of gum surfaces and solidifies over them. Over several days, this gel gradually releases the antibiotic medication.

  • PerioChip® – This chip is placed into the actual gum pocket after root planing procedure. PerioChip® slowly releases Chlorhexidine, a powerful antibacterial antiseptic. PerioChip® reduces pocket depth in most cases in periodontitis sufferers.

  • Actisite® – This thin strip is similar to dental floss and contains tetracycline hydrochloride. The thread is place temporarily directly between the tooth and gum to kill bacteria and reduce the depth of gum pockets. Several threads are sometimes placed for around 10 days to enhance the antibiotic effect.

  • Elyzol® – This metronidazole antibiotic comes in gel and strip form. It is unique because it is able to destroy parasites as well as oral bacteria.

  • Arestin® – This Minocycline antibiotic comes in mini capsules which are delivered into the gums after scaling and root planning.

Noticeable periodontal improvements are usually seen after systemic or oral antibiotic treatment. Your Periodontist or dentist will incorporate and recommend the necessary antibiotic treatments as necessary for the healing of your periodontal condition.

If you have any questions about periodontal disease or antibiotic treatments, please ask your dentist.

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We at Prosites sincerely appreciate the opportunity to design and host your new website. Your dedication to educating and serving your patients is evident by the excellent information and background your website provides to visitors. We salute your efforts in providing that extra level of communication and service that is so important to patients.

Lance V. McCollough President & CEO Prosites, Inc.

Dr. Carpenter,



So many times in business and life in general, we are pummeled with the negative. I just wanted to drop a quick positive note to let you know how pleased I am with yourself and the entire staff at M Street Dental. My entire family have been patients with you for many years. I don’t believe anyone will tell you they enjoy going to the dentist and I will confess I am no exception. M Street Dental however has always maintained a genuinely positive and friendly atmosphere where I feel as though I am among friends. This includes your entire staff. On Thursday, January 17th, I went into your clinic expecting to have a what was left of a tooth that had broken off extracted. To my pleasant surprise you have put me on a treatment plan to basically “resurrect” this tooth. Keep up the great work & kudos to you all.

Brian Buckingham

When I asked for an evaluation of my mouth, I thought I would probably lose all my remaining teeth, and start over. Remarkably you immediately removed the remains of 2 teeth and set up time the next day to make impressions. Your assistant made very good impressions, and made time the next day for your lab people to add to and repair my existing partial plates. A great job by all of you! The fit is amazing, and they work almost as well as normal teeth. They have needed no adjusting and I can eat green salad again, and apples! And the teeth that show in a smile look very natural. Thank all of you for a good job, well done. It is much appreciated! All done in 4 days!! Unbelievable! Thank you very much.

June Cheek

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